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Peptide Research Glossary: 20 Terms Every Researcher Should Know

The vocabulary behind COAs, product pages and published studies.

Peptide documentation uses a lot of shorthand. These are the terms you will meet most often.

Documentation terms

COA (Certificate of Analysis): a lab report for a specific batch showing test results. How to read one.

HPLC (high-performance liquid chromatography): a method that separates a sample's components and reports purity as the main peak's share of total peak area. HPLC explained.

Mass spectrometry (MS): measures molecular weight to confirm that the compound is what the label says.

Batch / lot number: the identifier that ties a vial to its specific test report.

Net peptide content: the share of the powder that is actual peptide, as opposed to water, salts and counter-ions. It is different from purity.

Counter-ion (such as TFA or acetate): a salt that remains from synthesis and purification.

Endotoxin: a bacterial contaminant sometimes tested for in higher-grade materials.

Handling terms

Lyophilized: freeze-dried into a stable powder.

Reconstitution: dissolving a lyophilized peptide in a diluent.

Bacteriostatic water: sterile water with 0.9% benzyl alcohol. Read more.

Half-life: the time for half of a compound to degrade or clear in a given system.

Pharmacology terms

Agonist: a compound that activates a receptor.

Secretagogue: a compound that prompts the release of another substance, such as growth hormone.

GHRH analog: a compound that mimics growth hormone-releasing hormone. GHRH vs ghrelin.

Ghrelin receptor (GHS-R1a): the receptor targeted by compounds such as Ipamorelin.

Angiogenesis: the formation of new blood vessels.

Telomerase: an enzyme that extends telomeres, the protective ends of chromosomes.

AMPK: a cellular energy sensor studied in metabolic research.

Mitochondria-derived peptide: a peptide encoded in mitochondrial DNA, such as MOTS-c.

Compliance term

RUO (research use only): products intended for laboratory research, not for human consumption. Read our policy.

Written for a research audience. Midas products are for laboratory research use only.

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Written for a research audience. No therapeutic claims. Midas Peptides products are sold for laboratory research use only — not for human consumption.

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