NAD+, Epithalon, MOTS-c, and SS-31 — the mechanisms researchers are studying in aging science.
Longevity is the fastest-growing area of peptide and compound research. Four names dominate the conversation — NAD+, Epithalon, MOTS-c, and SS-31 — each targeting a different mechanism of cellular aging. This is a research-context overview, not health advice.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to mitochondrial energy production, DNA repair, and sirtuin activity. Levels decline measurably with age, which is why researchers study whether restoring it affects energy metabolism and cellular aging. See the NAD+ research page.
Epithalon is a synthetic tetrapeptide studied for its relationship to telomerase activity and circadian regulation. Telomeres — the protective caps on chromosomes — shorten as cells divide, and Epithalon is one of the most-discussed compounds in that line of research. Explore Epithalon.
MOTS-c is encoded within mitochondrial DNA and studied as an "exercise-mimetic" — investigated for AMPK activation and metabolic-homeostasis pathways, the same signaling that exercise triggers. See MOTS-c.
SS-31 (elamipretide) is researched for binding cardiolipin in the inner mitochondrial membrane and reducing oxidative stress — a focus of research into how mitochondria age. See SS-31.
Three of these four center on the mitochondria — the cell's power plants — and the fourth on chromosomal protection. Together they map the major fronts of longevity research: energy, oxidative stress, and cellular lifespan.
Human outcome data in longevity research is still developing. These are research compounds, sold for laboratory use only — the science is the point, not a promise.
Every longevity compound at Midas is third-party tested with a published COA — here's how to read one. Browse the full longevity catalog.